Genetically encoded optical sensors for monitoring of intracellular chloride and chloride-selective channels activity
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منابع مشابه
Genetically Encoded Optical Sensors for Monitoring of Intracellular Chloride and Chloride-Selective Channel Activity
This review briefly discusses the main approaches for monitoring chloride (Cl(-)), the most abundant physiological anion. Noninvasive monitoring of intracellular Cl(-) ([Cl(-)]i) is a challenging task owing to two main difficulties: (i) the low transmembrane ratio for Cl(-), approximately 10:1; and (ii) the small driving force for Cl(-), as the Cl(-) reversal potential (E(Cl)) is usually close ...
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ژورنال
عنوان ژورنال: Frontiers in Molecular Neuroscience
سال: 2009
ISSN: 1662-5099
DOI: 10.3389/neuro.02.015.2009